Community Level Interventions to Improve Minority Health and Reduce Health Disparities (R01 - Clinical Trial Optional) | PAR 24 231

Opportunity Information: Apply for PAR 24 231

The National Institutes of Health (NIH) is soliciting applications under PAR-24-231, titled "Community Level Interventions to Improve Minority Health and Reduce Health Disparities (R01 - Clinical Trial Optional)." This is a discretionary grant opportunity using the NIH R01 research project grant mechanism, and its central goal is to fund research that develops and rigorously tests community-level interventions designed to improve minority health outcomes and reduce persistent health disparities. In practical terms, the focus is on interventions that operate at the community level rather than only at the individual patient level, meaning applicants are expected to address social, environmental, structural, or system factors in communities that contribute to unequal health outcomes.

The research scope emphasized by the NOFO is intervention development and evaluation. Projects should be designed to produce evidence about whether a community-level strategy works, for whom it works, and under what real-world conditions it can be implemented and sustained. Because the announcement is labeled "Clinical Trial Optional," applicants may propose studies that include a clinical trial component, but they are not required to do so. This flexibility allows for a range of designs, from community-based trials and pragmatic studies to other rigorous evaluation approaches that fit the intervention and setting.

Eligibility is broad and intentionally inclusive of many organization types that commonly work in or represent communities experiencing disparities. Eligible applicants listed in the source include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education); for-profit organizations other than small businesses; and small businesses. The NOFO also specifically calls out additional eligible applicant categories that reflect a strong emphasis on organizations embedded in underserved communities and institutions that serve minority populations. These include Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; regional organizations; eligible agencies of the federal government; Indian/Native American tribal governments other than federally recognized; and U.S. territories or possessions.

At the same time, the NOFO draws clear boundaries around foreign involvement. Non-domestic (non-U.S.) entities, meaning foreign organizations, are not eligible to apply. In addition, non-domestic components of U.S. organizations are not eligible to apply. The NOFO also states that foreign components, as defined by the NIH Grants Policy Statement, are not allowed. Taken together, these restrictions mean the work and the applicant organization must be U.S.-based, and the project cannot rely on foreign components as part of the proposed activities.

Key administrative details include that the funding activity category is health and the CFDA number is 93.307. The opportunity was created on June 10, 2024, and the original closing date listed is January 7, 2027, indicating a multi-year window during which applications may be accepted according to NIH submission cycles. The award ceiling shown is $1,000,000, which signals an upper bound on the amount that may be awarded under the opportunity (with actual budgets typically expected to align with project scope, NIH budget rules, and the specific aims proposed). The source information does not specify an expected number of awards, leaving that field blank, which generally suggests awards will depend on application volume, merit, and available appropriations.

Overall, this NOFO is best understood as an NIH R01 opportunity aimed at building practical, evidence-based solutions that work at the community level to close gaps in health outcomes affecting minority populations. Competitive applications will generally be those that are grounded in the realities of the community setting, structured to test an intervention with a credible evaluation plan, and positioned to generate findings that can inform broader efforts to reduce health disparities.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Community Level Interventions to Improve Minority Health and Reduce Health Disparities (R01 - Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.307.
• This funding opportunity was created on 2024-06-10.
• Applicants must submit their applications by 2027-01-07.
• Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 24 231

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