Opportunity Information: Apply for RFA NS 18 026
The NINDS Morris K. Udall Centers of Excellence for Parkinsons Disease Research (P50 Clinical Trial Optional) funding opportunity (RFA-NS-18-026) is a National Institutes of Health grant program run through the Department of Health and Human Services, specifically the National Institute of Neurological Disorders and Stroke (NINDS). Its main purpose is to support a coordinated national network of specialized research Centers focused on Parkinsons disease (PD). These Centers are expected to work both independently and collaboratively, with the broader objective of clarifying the causes of PD and accelerating the discovery of better treatments. Beyond producing strong science, the program is designed to create visible national leaders in PD research that can drive progress more quickly than isolated projects typically can.
A core feature of the Udall Centers model is its emphasis on synergy and interdisciplinary integration. Applicants are expected to build a Center around a clear, unifying research theme that addresses a major, high-priority challenge in PD. The theme is not meant to be a vague umbrella; it should be specific enough to shape the Center's projects and shared resources in a way that makes the whole program more impactful than the sum of its parts. NINDS explicitly prioritizes innovative and integrative work with high potential for discovery, and it expects applicants to demonstrate that the Center structure is essential. In practical terms, reviewers will look for strong scientific interdependence among projects and cores, where the research goals could not realistically be achieved without the shared infrastructure, coordination, and collaboration that a Center provides.
Structurally, the FOA requires at least three research projects as the backbone of each proposed Center. These projects should be aligned with the Center theme and collectively advance understanding of PD etiology, disease mechanisms (pathogenesis), and/or treatment approaches. Studies on related synucleinopathies can be included, but only if they directly help resolve the central PD research challenge defined by the application. In other words, related-disease work is allowed when it strengthens the PD focus rather than diluting it.
In addition to the research projects, the FOA requires a set of cores that provide shared capabilities and are demonstrably essential to the science. Each scientific core must be critical to at least two of the proposed research projects, which is a built-in way of enforcing integration and preventing cores from being add-ons that serve only one lab or aim. An Administrative Core is also required to manage governance, coordination, communication, and overall Center operations. Taken together, the projects and cores are expected to operate like a tightly connected program, with shared strategies, shared methods or resources where appropriate, and clear collaborative advantages that speed progress.
The Udall Center concept also includes responsibilities that go beyond conducting research. Each application must include a mission statement along with a concrete plan for career enhancement. This career enhancement component is meant to strengthen the development of trainees and investigators affiliated with the Center through organized activities, mentorship, and professional development opportunities. The intent is to use the Center as a training and career-advancement environment, helping build the next generation of PD researchers while also supporting the growth of current investigators within the Center.
Another required element is an outreach plan that connects the Center to the local Parkinsons patient and advocacy community. The FOA calls for effective outreach and dissemination of Udall Center research results, meaning the Center should have a practical strategy for two-way engagement: sharing findings in accessible ways and building relationships with patient and advocacy stakeholders. This positions Udall Centers not only as scientific hubs but also as local resources that help translate research progress into understandable information and foster community trust and involvement.
Leadership expectations are also clearly stated. The Udall Center Director (the PD/PI) must be an established scientific leader with demonstrated expertise, strong management ability, and visionary leadership skills. Since the program depends on coordination across multiple projects and shared cores, the PD/PI is expected to guide scientific direction, maintain integration, and ensure the Center functions as a unified enterprise rather than a loose collection of separate studies.
From an administrative standpoint, this is a discretionary NIH grant using the P50 Center mechanism, and it is labeled "Clinical Trial Optional," meaning clinical trials may be included but are not required. The activity category is Health, and the CFDA number listed is 93.853. Eligibility is broad and includes various levels of government entities, public and private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), for-profit organizations (other than small businesses), small businesses, tribal governments and tribal organizations, and other applicants as described in the FOA's additional eligibility language. The opportunity record indicates an expected two awards, a creation date of October 25, 2018, and an original closing date of January 4, 2019, with an award ceiling listed as 0 (which typically signals that applicants should rely on the FOA text and NIH budget guidance rather than a single posted cap in the summary field).
Overall, this FOA is aimed at building highly integrated, theme-driven Centers that can move the field forward faster through collaboration, shared resources, and coordinated leadership. The strongest applications under this model are typically those that define a focused and urgent PD research challenge, design multiple projects that truly depend on one another, justify cores that enable at least two projects each, and show serious commitment to both workforce development and meaningful patient/community outreach.Apply for RFA NS 18 026
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "NINDS Morris K. Udall Centers of Excellence for Parkinsons Disease Research (P50 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853.
- This funding opportunity was created on Oct 25, 2018.
- Applicants must submit their applications by Jan 04, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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